Transplantation of ex vivo cultured limbal epithelial stem cells: a review of techniques and clinical results

AJ Shortt, GA Secker, MD Notara, GA Limb… - Survey of …, 2007 - Elsevier
Ex vivo cultured limbal epithelial stem cells have been used successfully to treat corneal
limbal stem cell deficiency. We identified 17 reports of the application of this novel cell …

Corneal stem cells in review

JT Daniels, JKG Dart, SJ Tuft… - Wound repair and …, 2001 - Wiley Online Library
The cornea provides the eye with protection and the refractive properties essential for visual
acuity. The transparent epithelium is highly specialized with basal and stratified squamous …

[HTML][HTML] Changes in collagen orientation and distribution in keratoconus corneas

KM Meek, SJ Tuft, Y Huang, PS Gill… - … & visual science, 2005 - arvojournals.org
purpose. To map the collagen orientation and relative distribution of collagen fibrillar mass
in keratoconus corneal buttons. methods. Structural analysis was performed by obtaining …

[HTML][HTML] TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease

MP Fautsch, ED Wieben, KH Baratz… - Progress in retinal and …, 2021 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in
the elderly. Since the first description of an association between FECD and common …

Prognostic factors for the progression of keratoconus

SJ Tuft, LC Moodaley, WM Gregory, CR Davison… - Ophthalmology, 1994 - Elsevier
Conclusions: The progression of keratoconus to a stage where penetrating keratoplasty (PK)
is required for visual rehabilitation has considerable implications for affected patients. To …

Characterization of the limbal epithelial stem cell niche: novel imaging techniques permit in vivo observation and targeted biopsy of limbal epithelial stem cells

AJ Shortt, GA Secker, PM Munro, PT Khaw, SJ Tuft… - Stem …, 2007 - academic.oup.com
It is anticipated that stem cell (SC) therapy will enable the regeneration of diseased tissues
and organs. Understanding SC niches is an essential step toward realizing this goal. By …

Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts

N Ardjomand, S Hau, JC McAlister, C Bunce… - American journal of …, 2007 - Elsevier
PURPOSE: To compare visual function after deep anterior lamellar keratoplasty (DALK) with
visual function after penetrating keratoplasty (PK) for keratoconus and correlate this with …

Acute corneal hydrops in keratoconus

SJ Tuft, WM Gregory, RJ Buckley - Ophthalmology, 1994 - Elsevier
Purpose: To determine the clinical factors associated with the development of acute corneal
hydrops and its subsequent outcome. Methods: The authors identified 147 eyes (124 …

Ex vivo expansion and transplantation of limbal epithelial stem cells

AJ Shortt, GA Secker, MS Rajan, G Meligonis, JK Dart… - Ophthalmology, 2008 - Elsevier
OBJECTIVE: To determine, using objective measures, the outcome of ex vivo cultured limbal
epithelial stem cell (LESC) transplantation performed in compliance with good …

Clinical features of atopic keratoconjunctivitis

SJ Tuft, DM Kemeny, JKG Dart, RJ Buckley - Ophthalmology, 1991 - Elsevier
The clinical spectrum of ocular disease in 37 patients with atopic keratoconjunctivitis (AKC)
is described. Patients typically had a severe blepharoconjunctivitis. Associated corneal …