[HTML][HTML] The toxic and stress responses of cultured human retinal pigment epithelium (ARPE19) and human glial cells (SVG) in the presence of triamcinolone

CK Yeung, KP Chan, SWY Chiang… - … & visual science, 2003 - iovs.arvojournals.org
purpose. To compare the cytotoxic effect of TA on human retinal pigment epithelium
(ARPE19) and human glial (SVG) cells over a range of concentrations and durations of …

[HTML][HTML] HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH

POS Tam, TK Ng, DTL Liu, WM Chan… - … & visual science, 2008 - tvst.arvojournals.org
purpose. Mapping the genes for age-related macular degeneration (AMD) had not been
successful until recent genome-wide association studies revealed Tyr402His in CFH and …

[HTML][HTML] Multiple gene polymorphisms in the complement factor h gene are associated with exudative age-related macular degeneration in chinese

TK Ng, LJ Chen, DTL Liu, POS Tam… - … & visual science, 2008 - iovs.arvojournals.org
purpose. Variants in the complement factor H (CFH) gene have been shown to be strongly
associated with age-related macular degeneration (AMD). In this study, sequence …

Genes in the high-density lipoprotein metabolic pathway in age-related macular degeneration and polypoidal choroidal vasculopathy

K Liu, LJ Chen, TYY Lai, POS Tam, M Ho, SWY Chiang… - Ophthalmology, 2014 - Elsevier
Purpose To investigate the associations of genetic variants in the high-density lipoprotein
(HDL) metabolism pathway with neovascular age-related macular degeneration (AMD) and …

[HTML][HTML] Compound heterozygosity of two novel truncation mutations in RP1 causing autosomal recessive retinitis pigmentosa

LJ Chen, TYY Lai, POS Tam… - … & Visual Science, 2010 - iovs.arvojournals.org
Purpose.: To evaluate the phenotypic effects of two novel frameshift mutations in the RP1
gene in a Chinese pedigree of autosomal recessive retinitis pigmentosa (ARRP). Methods …

[HTML][HTML] Association of CTLA-4 and IL-13 gene polymorphisms with Graves' disease and ophthalmopathy in Chinese children

KKL Chong, SWY Chiang, GWK Wong… - … & visual science, 2008 - arvojournals.org
purpose. The frequency of childhood Graves' disease (GD) in Hong Kong Chinese is among
the highest in the world but childhood Graves' ophthalmopathy (GO) appears to have milder …

[HTML][HTML] SNP rs1533428 at 2p16. 3 as a marker for late-onset primary open-angle glaucoma

LJ Chen, POS Tam, DYL Leung, AH Fan… - Molecular …, 2012 - ncbi.nlm.nih.gov
Purpose To investigate the associations between gene variants in cholesterol 24S-
hydroxylase (CYP46A1), LIM homeobox transcription factor 1-beta (LMX1B), plexin domain …

[HTML][HTML] Ethnic specific association of the CAV1/CAV2 locus with primary open-angle glaucoma

SS Rong, LJ Chen, CKS Leung, K Matsushita, L Jia… - Scientific reports, 2016 - nature.com
A single-nucleotide polymorphism (SNP) rs4236601 at the CAV1/CAV2 locus is associated
with primary open-angle glaucoma (POAG). Rs4236601 is common in Caucasians but rare …

[HTML][HTML] Differentiation of exudative age-related macular degeneration and polypoidal choroidal vasculopathy in the ARMS2/HTRA1 locus

XY Liang, TYY Lai, DTL Liu, AH Fan… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: To differentiate the associations of exudative age-related macular degeneration
(AMD) and polypoidal choroidal vasculopathy (PCV) with the ARMS2/HTRA1 locus …

Associations of the C2-CFB-RDBP-SKIV2L locus with age-related macular degeneration and polypoidal choroidal vasculopathy

K Liu, LJ Chen, POS Tam, Y Shi, TYY Lai, DTL Liu… - Ophthalmology, 2013 - Elsevier
PURPOSE: To investigate the associations of the C2-CFB-RDBP-SKIV2L region with
neovascular age-related macular degeneration (AMD) and polypoidal choroidal …