Background: Evidence from both clinical and experimental research indicates that the
immune-brain interaction plays a pivotal role in the pathophysiology of depression. A multi …

Aims The NLRP 3 inflammasome is a cytoplasmic multiprotein complex of the innate
immune system that regulates the cleavage of interleukin‐1β and interleukin‐18 precursors …

Depression is often preceded by exposure to stressful life events. Chronic stress causes
perturbations in the immune system, and up-regulates production of proinflammatory …

High mobility group box 1 (HMGB1) has been implicated as a key factor in several
neuroinflammatory conditions. Our previous study suggested that the release of central …

This study was designed to evaluate the efficacy, tolerability, and sequential administration
of abiraterone acetate (AA) and enzalutamide (Enz) for metastatic castration-resistant …

Depression disorder is a common mental illness, of which the pathogenesis is not well
understood. Studies suggest that immunity imbalance and up-regulation of pro-inflammatory …

Emerging evidence suggests that neuroinflammation and oxidative stress may be major
contributors to major depressive disorder (MDD). Patients or animal models of depression …

Purpose: To assess the incidence rate of myopia, refractive change, and the effects of
influencing factors on a group of highly selected senior high school students in an Aviation …

Background. In recent decades, the prevalence rate of myopia has markedly increased,
especially among teenagers. Our purpose was to determine the incidence of myopia and …

AIM To characterize peripheral refraction and its relationship with myopia development in a
selected group of male teenage Chinese students. METHODS This 2-year prospective …