[HTML][HTML] HDL from an Alzheimer's disease perspective
Evidence from human studies, animal models, and bioengineered arteries supports the
hypothesis that HDL protects against cerebrovascular dysfunction in Alzheimer's disease …
hypothesis that HDL protects against cerebrovascular dysfunction in Alzheimer's disease …
[HTML][HTML] An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
Immunochemotherapy combines a chemotherapeutic agent with an immune-modulating
agent and represents an attractive approach to improve cancer therapy. However, the …
agent and represents an attractive approach to improve cancer therapy. However, the …
Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid‐Nanoparticle Components for Therapeutic and Vaccine Applications
Lipid nanoparticles (LNPs) have proven a successful platform for the delivery of nucleic acid
(NA)‐based therapeutics and vaccines, with the ionizable lipid component playing a key role …
(NA)‐based therapeutics and vaccines, with the ionizable lipid component playing a key role …
Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy
A simple PEGylated peptidic nanocarrier, PEG 5000-lysyl-(α-Fmoc-ε-Cbz-lysine) 2 (PLFCL),
was developed for effective co-delivery of doxorubicin (DOX) and dasatinib (DAS) for …
was developed for effective co-delivery of doxorubicin (DOX) and dasatinib (DAS) for …
Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels
J Robert, EB Button, B Yuen, M Gilmour, K Kang… - Elife, 2017 - elifesciences.org
Amyloid plaques, consisting of deposited beta-amyloid (Aβ), are a neuropathological
hallmark of Alzheimer's Disease (AD). Cerebral vessels play a major role in AD, as Aβ is …
hallmark of Alzheimer's Disease (AD). Cerebral vessels play a major role in AD, as Aβ is …
Targeted delivery of doxorubicin by folic acid-decorated dual functional nanocarrier
Doxorubicin (DOX) is one of the most commonly used antineoplastic agents, but its clinical
application is oftentimes coupled with severe side effects. Selective delivery of DOX to …
application is oftentimes coupled with severe side effects. Selective delivery of DOX to …
PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers
Paclitaxel (PTX) is one of the most effective chemotherapeutic agents for a wide spectrum of
cancers, but its therapeutic benefit is often limited by severe side effects. We have …
cancers, but its therapeutic benefit is often limited by severe side effects. We have …
Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy
Two novel prodrug polymers POEG-b-PSSDas (redox-sensitive) and POEG-b-PCCDas
(redox-insensitive), which consist of poly (oligo (ethylene glycol) methacrylate)(POEG) …
(redox-insensitive), which consist of poly (oligo (ethylene glycol) methacrylate)(POEG) …
Effect of atropine, orthokeratology and combined treatments for myopia control: a 2-year stratified randomised clinical trial
S Xu, Z Li, W Zhao, B Zheng, J Jiang, G Ye… - British Journal of …, 2023 - bjo.bmj.com
Purpose To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and
combined treatment on myopia. To explore the factors influencing the efficacy. Methods An …
combined treatment on myopia. To explore the factors influencing the efficacy. Methods An …
Short-term effects of atropine combined with orthokeratology (ACO) on choroidal thickness
W Zhao, Z Li, Y Hu, J Jiang, W Long, D Cui… - Contact Lens and …, 2021 - Elsevier
Purpose To analyse the one-month change in subfoveal choroidal thickness (SFChT) of
myopic children treated with 0.01% atropine, orthokeratology (OK), or their combination …
myopic children treated with 0.01% atropine, orthokeratology (OK), or their combination …