Subgenome parallel selection is associated with morphotype diversification and convergent crop domestication in Brassica rapa and Brassica oleracea
F Cheng, R Sun, X Hou, H Zheng, F Zhang, Y Zhang… - Nature …, 2016 - nature.com
Brassica species, including crops such as cabbage, turnip and oilseed, display enormous
phenotypic variation. Brassica genomes have all undergone a whole-genome triplication …
phenotypic variation. Brassica genomes have all undergone a whole-genome triplication …
Optical coherence tomography angiography discerns preclinical diabetic retinopathy in eyes of patients with type 2 diabetes without clinical diabetic retinopathy
D Cao, D Yang, Z Huang, Y Zeng, J Wang, Y Hu… - Acta …, 2018 - Springer
Aims To investigate changes in retinal vascular plexuses and choriocapillaris in patients
with type 2 diabetes mellitus (DM2) without diabetic retinopathy (DR) and healthy controls …
with type 2 diabetes mellitus (DM2) without diabetic retinopathy (DR) and healthy controls …
Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studies
F Tan, X Shen, D Wang, G Xie, X Zhang, L Ding, Y Hu… - Lung cancer, 2012 - Elsevier
Icotinib, one of the leading compounds selected from our compound library, was found to be
a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) …
a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) …
Early retinal neurovascular impairment in patients with diabetes without clinically detectable retinopathy
Y Zeng, D Cao, H Yu, D Yang, X Zhuang… - British Journal of …, 2019 - bjo.bmj.com
Aims To investigate the function and the corresponding neurovascular structures in patients
with diabetes without clinically detectable retinopathy. Methods Sixty-six patients with type 2 …
with diabetes without clinically detectable retinopathy. Methods Sixty-six patients with type 2 …
Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitors
S Hu, G Xie, DX Zhang, C Davis, W Long, Y Hu… - Bioorganic & medicinal …, 2012 - Elsevier
Crown ether fused anilinoquinazoline analogues were synthesized as novel epidermal
growth factor receptor (EGFR) tyrosine kinase inhibitors. Representative compounds …
growth factor receptor (EGFR) tyrosine kinase inhibitors. Representative compounds …
Comparison of expression profiling of circular RNAs in vitreous humour between diabetic retinopathy and non-diabetes mellitus patients
M He, W Wang, H Yu, D Wang, D Cao, Y Zeng, Q Wu… - Acta …, 2020 - Springer
Aims To compare circular (circRNA) expression levels in the vitreous humour between PDR
(proliferative diabetic retinopathy) and the control groups. Methods The present study …
(proliferative diabetic retinopathy) and the control groups. Methods The present study …
A transposon insertion in FLOWERING LOCUS T is associated with delayed flowering in Brassica rapa
Long days and vernalization accelerate the transition from vegetative growth to reproductive
growth in Brassica rapa. Bolting before plants reach the harvesting stage is a serious …
growth in Brassica rapa. Bolting before plants reach the harvesting stage is a serious …
EBD: an eye biomarker database
Motivation Many ophthalmic disease biomarkers have been identified through
comprehensive multiomics profiling, and hold significant potential in advancing the …
comprehensive multiomics profiling, and hold significant potential in advancing the …
[HTML][HTML] Shared genetic architecture between the two neurodegenerative diseases: Alzheimer's disease and glaucoma
C Zheng, S Liu, X Zhang, Y Hu, X Shang… - Frontiers in aging …, 2022 - frontiersin.org
Background: Considered the representatives of neurodegenerative diseases, Alzheimer's
disease and glaucoma are complicated progressive neuropathies affected by both genetic …
disease and glaucoma are complicated progressive neuropathies affected by both genetic …
[HTML][HTML] Comprehensive analysis of vitreous chemokines involved in ischemic retinal vein occlusion
Y Zeng, D Cao, H Yu, X Zhuang, D Yang, Y Hu… - Molecular …, 2019 - ncbi.nlm.nih.gov
Methods The vitreous humor was collected at the start of 23-gauge pars plana vitrectomy
from patients with ischemic RVO and patients with idiopathic preretinal membranes (PRMs) …
from patients with ischemic RVO and patients with idiopathic preretinal membranes (PRMs) …