The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis

GS Baarsma, E La Hey, E Glasius, J De Vries… - American journal of …, 1987 - Elsevier
GS Baarsma, E La Hey, E Glasius, J De Vries, A Kijlstra
American journal of ophthalmology, 1987Elsevier
We determined the serum angiotensin converting enzyme and lysozyme levels in 221
patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and
lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In
patients with uveitis who had an angiotensin converting enzyme level above 50 units/1
(mean+ 2 SD), the sensitivity of the test was 84%, the specificity was 95%, and the predictive
value was 47%. In these same patients the sensitivity was 60% for a lysozyme level above 8 …
We determined the serum angiotensin converting enzyme and lysozyme levels in 221 patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In patients with uveitis who had an angiotensin converting enzyme level above 50 units/1 (mean + 2 S.D.), the sensitivity of the test was 84%, the specificity was 95%, and the predictive value was 47%. In these same patients the sensitivity was 60% for a lysozyme level above 8 mg/1 (mean + 2 S.D), the specificity was 76%, and the predictive value was 12%.
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