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Scientific correspondence
Increase of macrophage migration inhibitory factor in sera of patients with iridocyclitis

Abstract

AIMS To determine whether macrophage migration inhibitory factor (MIF) levels were increased in sera of the patients with iridocyclitis.

METHODS Sera were obtained from 41 patients with acute iridocyclitis, 13 patients with chronic iridocyclitis, and 44 healthy control subjects. MIF levels were determined by a human MIF ELISA.

RESULTS The average levels of MIF in the sera of patients with both acute and chronic iridocyclitis were significantly higher than that of healthy subjects.

CONCLUSION Uveitis induces the elevation of serum MIF, which may affect various inflammatory symptoms in uveitis.

  • migration inhibitory factor
  • iridocyclitis

https://doi.org/10.1136/bjo.84.12.1423

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