Editor,—Hydroxyurea is an antineoplastic agent used in the treatment of various myelproliferative conditions and severe psoriasis. Documented skin manifestations from long term therapy with hydroxyurea include icthyosis, a dermatomyositis-like eruption on the dorsal hands, facial erythema, and accelerated development of premalignant and malignant skin lesions.1-5 Our patient is the first described case of a cutaneous manifestation of long …